

As you progress these enemies will evolve and learn new tricks to maintain the challenge. If you're lucky, flies and lava will be the most of your troubles, but most likely, your move-and-shoot abilities will be tested by flaming, headless torsos or blood-vomiting gluttons. Although the path may be different, there are still a few familiar stops along the way.

The randomized structure of each floor means no two play sessions are exactly alike. Bite the dust and you'll have to start the whole game over again. Keys, bombs, and other items become available as you progress, but no matter how strong you become, death remains a constant companion during this challenging journey. Isaac's initial attack is weaponized crying-meaning he can strike foes from afar by blinking out crocodile-sized tears in four directions. A boss chamber lies at the end of the maze and houses a gruesome fiend that Isaac must overcome before descending to the next floor. This floor and all subsequent floors are divided into single, connecting rooms that contain monsters or items. The door will also open by using the Dad's Key usable item.Isaac's descent begins in a basement. If you have a Golden Key (achieved by killing two Angel mini-bosses in Angel Rooms), then the door will open and you will be able to fight the Mega Satan boss fight. After beating ? for the first time, a golden door will appear in the starting room of The Chest floor. The final boss of The Chest will always be ?. Unlocked after beating It Lives! It is also possible to access it early on through an Angel Room after beating Mom's Heart/It Lives! The final boss of the Cathedral will always be Isaac.Ĭan only be entered by beating Isaac in The Cathedral and touching The Chest while having The Polaroid item.

The door will also open by using the Dad's Key usable item. After beating The Lamb for the first time, a golden door will appear in the starting room of the Dark Room floor. The final boss of the Dark Room will always be The Lamb. Can only be entered by beating Satan in Sheol and touching the chest while having The Negative item.
